Estrogen, Stress and Cognition Literature Review
Is sex-drug fuckery connected to inappropriate behavior?
Estrogen in prefrontal cortex blocks stress-induced cognitive impairments in female rats (2015)
This paper looks at the role of estrogen in managing stress for female rats. This has implications for what happens when a female has reduced or impaired estrogen metabolism, especially in the prefrontal cortex, which is the seat of judgment.
Sex in the brain: hormones and sex differences (2016)
Discussion of how hormones act throughout the brain on both genomic and non-genomic receptors (e.g. membrane androgen receptors) and the effects this has on a wide range of neurological functions and responses to other substances including opiates.
Sex-dependent differences in voluntary physical activity - PubMed (nih.gov) (2017)
What chemicals you are exposed to in childhood shapes your adult responses to sex hormones, which in turn shapes your physical activity, predisposing you to more or less tendency to voluntary physical activity. Could his childhood medicalization be why Jazz Jennings is obese as an adult?
Estrogen promotes stress sensitivity in a prefrontal cortex-amygdala pathway (2010)
“These data demonstrate both independent effects of estrogen on pyramidal cell morphology and effects that are interactive with stress, with the BLA-projecting neurons being sensitive to both kinds of effects. “ Could this explain why Anthony Martucci behaved so poorly at #letwomenspeak NYC? Did estrogen remodel his neuronal pyramidal system altering his behavioral responses to psychologcial stress of seeing women who dared to disagree with his bullshit?
Brain estrogen alters the effects of the antidepressant sertraline in middle-aged female and male mice (2020)
“Our results showed that depletion of brain estrogen increased depressive-like behavior in females, and elevated brain estrogen reduced depression-like behavior, regardless of sex.” “The present data suggest that brain estrogen alters depressive-like behaviors and changes the effectiveness of antidepressants in middle-aged mice, regardless of sex.” Are doctors who push transition at the start of treatment for depressed trans-identifying individuals, as was recommended by the Glitterature review authors, actually sabotaging the effectiveness of antidepressants? Are doctors who prescribe testosterone to depressed women sabotaging their recovery as well? Suicide prevented, I guess. Dysphoria cured. Anthony Martucci’s estrogenized brain definitely reduced his depression-like behavior at #letwomenspeak NYC.
“…the suppressive effects of testosterone on cortical monoamine oxidase-A that were observed could have bearing on the increased incidence of cognitive deficits and symptoms of depression and anxiety that are repeatedly observed in males in conditions of hypogonadalism related to aging…” Once again, are doctors sabotaging the recovery of mentally ill patients by screwing around with their hormones for a cosmetic purpose?
"Could this explain why Anthony Martucci behaved so poorly at #letwomenspeak NYC"
I often wonder if MTFs behave so aggressively and in my opinion deranged because of the effect of estrogen on male bodies.
Testosterone doesn't directly inspire violence in the male, it makes the male very conscious of hierarchy, and then the (young, unfinished, low-status) male acts out violently in pursuit of status. I am curious to know more about its behavioral effects on these poor young women taking it. Same with males and estrogen. How does it affect other risk-taking behaviors?