Puberty Blockers Dam the River as the Doctors Damn the Consequences
The Role of Luteinizing Hormone in Central Nervous System Development
The propaganda regarding puberty blockers is that this drug class, gonadotropin-releasing hormone analogs, drugs which mimic the effect of GNRH in the body and are therefore also hormones, stop the natural puberty process. Then doctors swoop in and provide cross-sex hormones which enable the appearance of normal cross-sex pubertal development. We’re told that this means that they just switched over and therefore they had a “normal puberty.” This line of stupidity is pushed by people who invariably have no actual idea how this drug works in the body and the cascade of suppression of hormones beyond well-known sex hormones it creates. Quite often, they will even push the fantasy that GNRH-analogs are somehow binding to the estrogen/androgen receptors and blocking these hormones that way.
They do not understand that the river is being dammed far upstream of sex hormones, nor do they take a moment to contemplate that this complex, cyclical, pulsatile hormonal dance has evolved for millions upon millions of years, in tandem with every organ system in our body. You cannot just swap that out, suppressing 5 hormones and only supplementing with one or two, input periodically as a bolus or continuously as an implant, and expect there to be no consequences. When Down Syndrome patients are treated with GNRH to improve cognition, they are provided with a pump that pushes a pulsatile dose of GNRH, because it is not enough to give the plant light; the plant needs day and night to bloom.
Puberty blockers suppress the maturation of brain areas critically important to cognition, including the pituitary, the hippocampus, and the hypothalamus. This in turn prevents the pituitary from producing the normal levels of two hormones rarely considered significant by the sex lobotomists: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These two hormones, in a normal puberty, then cause the gonads to develop and to start producing estrogen, progesterone, and testosterone. When doctors suppress the release of FSH and LH, this is what prevents the gonads from developing to the point of producing normal levels of estrogen, progesterone and testosterone, which are all released cyclically. The plant needs day and night to bloom.
I have yet to hear of a person who was puberty suppressed and provided with cross-sex hormones claim that their doctor ever attempted to replace FSH and LH. And why would they? They have no cosmetic impact and so the presence would serve only to thwart the puberty blockers and mature the gonad that puberty blockers leave stunted and neutered. There is an extremely complex and dynamic relationship between all of these hormones, neurotransmitters generally, and therefore neurodevelopmental processes. This relationship is poorly understood and the research into it is foundational and in its infancy. “The GnRH release depends on the complex and co-ordinated interrelationships among gonadal steroids, pituitary gonadotropins and neuroactive transmitters, such as the noradrenaline, dopamine, opioid peptides (beta-endorphin), acetylcholine, serotonin, gamma-aminobutyrric acid, corticotropin releasing hormone and neuropeptide Y. The interplay of these control mechanisms is governed by peripheral feedback signals; as well as the input from higher brain centers they may modify the GnRH secretion.” (Stomati 1998).
Luteinizing hormone, specifically age-related dysregulation, is implicated in neurological diseases of aging. “Of note, increasing evidence supports extra-gonadal roles for LH within the CNS, particularly as it relates to cognition and plasticity in aging and age-related degenerative diseases such as Alzheimer's disease (AD). However, despite increasing evidence that supports a link between this hormone and CNS function, the mechanisms underlying LH action within the brain and how they influence cognition and plasticity during the lifespan is poorly understood and, in fact, often in conflict.” (Mey 2021) This implies that it is foundationally important to the development and maintenance of function of the central nervous system earlier in development. What this means, in my opinion, is that children deprived of this hormone via puberty blockers during critical periods of development are being put at increased risk of neurodevelopmental/neurodegenerative diseases of aging, possibly far earlier in life than they typically onset.
These hormones are directly implicated in the day to day behavior, such as something called the “basic-rest-activity-cycle” (BRAC). When disrupted, it is likely that for a gender dysphoric patient, a neuroendocrine behavioral disorder will be blamed on “dysphoria” or “depression,” when in fact it is the direct result of luteinizing hormone deficiency during a critical developmental window. “This BRAC entrainment of pulsatile LH secretion is also utilized as a model to demonstrate how the BRAC may modulate the activity of various physiological functions via relatively direct mechanisms, secondary interactions, or entrainment of tissue with its own intrinsic pacemaker activity. The physiological function of the BRAC is discussed relative to this entrainment of pulsatile [luteinizing hormone] release.” (Rasmussen 1986)
Other authors confirm that the complex, pulsatile, interrelated regulatory dance of GNRH, LH and other hormones and neurotransmitters in the brain have a direct impact on behavior, which is not understood and is frankly not being considered, as far as I can tell, and I’ve looked into this issue in significant depth, in this quest to cut and drug a boy into a cosmetic facsimile of a girl. They are breeding them like dogs, and dog breeding has created many breed-specific health complications, such as dermoid sinus in Rhodesian Ridgebacks. When this drug is being given to change behavior - specifically, we are told, to prevent the behavior of suicide - it is astonishing that the behavioral impact of neuroendocrine fuckery is never on the table. “LH and hCG [human chorionic gonadotropin] also induce several behavioral and other changes that are associated with the hippocampus, which contains the highest density of LH/hCG receptors. Many of the behavioral changes induced by hCG in rats parallel those in pregnant women. Some of these behavioral effects are correlated with changes of eicosanoid metabolism induced by LH and hCG in the brain.” (Lei 2001)
The reason for all this is the gender doctors are acting outside of their competence, which is an ethical violation. They need to be sued and cross-examined, on video, during deposition, so that the fact that they were acting far outside their competence, that they had no idea of any of the obvious implications of what they were attempting to do, is exposed for all to see, ESPECIALLY a jury. Then medical boards such as in Florida will be forced to act, or the unethical hacks will be forced to settle to attempt to keep their incompetence a secret.
However, I highly advise anyone in such a pursuit to file the ethics and malpractice complaints with the licensing boards prior to accepting any settlement and signing any nondisclosure agreements. If it is not specifically in the agreement that you represent that you have not already filed such a complaint, you are likely free to tell the relevant bodies and then promise not to tell a soul in exchange for cash. Though check with your attorney.
It is obscene that they are experimenting on healthy kids cosmetically when we know so little about the essential neurodevelopmental functions of these hormones. They are playing God. The day of judgment for the sex lobotomists is coming. There is absolutely no way in hell that this nonsense will not have negative health consequences which were not predicted by these incompetent, sex-obsessed buffoons in white coats, but are obvious in retrospect.
References:
Lei, ZM. “Neural actions of luteinizing hormone and human chorionic gonadotropin. “Seminars in Reproductive Medicine. 2001;19(1):103-9. Accessed 1/25/2023. doi: 10.1055/s-2001-13917.
Mey, Megan et al. “Luteinizing hormone and the aging brain.” Vitamins and Hormones. 2021;115:89-104. doi: 10.1016/bs.vh.2020.12.005. Accessed 1/25/2023
Rasmussen, DD. “Physiological interactions of the basic rest--activity cycle of the brain: pulsatile luteinizing hormone secretion as a model.” Psychoneuroendocrinology. 1986;11(4):389-405. doi: 10.1016/0306-4530(86)90001-6. Accessed 1/25/2023
Stomati, M. et al. “Contraception as prevention and therapy: sex steroids and the brain.” The European Journal of Contraception and Reproductive Healthcare. 1998 Mar;3(1):21-8. doi: 10.3109/13625189809167481.Contraception as prevention and therapy: sex steroids and the brain - PubMed (nih.gov). Accessed 1/25/2023
Fascinating, as usual. The parallels between breeding dogs and what we now see happening to children and young adults is horrifying and makes perfect sense. I do think that all doctors have a God complex to varying degrees but playing God will have very serious and ugly consequences.
Great work as usual. Shame on the medical profession for the harm they are knowingly doing to healthy children